反応式
[CH3:1]CCCCC.C[Si](C=[N+]=[N-])(C)C.[F:14][C:15]1[C:16]([C:21]([OH:23])=[O:22])=[N:17][CH:18]=[CH:19][CH:20]=1>C(O)C.CN(C=O)C>[F:14][C:15]1[C:16]([C:21]([O:23][CH3:1])=[O:22])=[N:17][CH:18]=[CH:19][CH:20]=1参加物
5
実験手順
A hexane solution (3 mL) of 2 M trimethylsilyldiazomethane was added to a benzene/methanol mixed solvent (1/1, 12 mL) of 3-fluoropyridine-2-carboxylic acid (250 mg), and stirred at room temperature for 30 minutes. The solvent was evaporated off under reduced pressure from the reaction solution, and the resulting residue was purified through silica gel column chromatography (chloroform/methanol=40/1) to obtain the entitled compound (238 mg).
後処理
- customThe solvent was evaporated off under reduced pressure from the reaction solution
- customthe resulting residue was purified through silica gel column chromatography (chloroform/methanol=40/1)
出典と根拠
- ORDレコード
- ord-897de591f8e845dead7024a6fcef2167
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07566781B2
関連ノート
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