Hydrazine → 3-Phenylpropanehydrazide

HRID 230788

反応式

HRID 230788 の反応式
[C:1]([O:11]C)(=O)/[CH:2]=[CH:3]/[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH2:13][NH2:14]>CO>[C:4]1([CH2:3][CH2:2][C:1]([NH:13][NH2:14])=[O:11])[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

参加物

4

反応物 2

HCID 9321HydrazineHCID 637520Methyl Cinnamate

生成物 1

HCID 2493483-Phenylpropanehydrazide

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

Methyl trans-cinnamate (1.0 g) and hydrazine (1.2 mL) were heated in methanol (25 mL) at 60° C. for 20 hours. The reaction solution was concentrated under reduced pressure, and the resulting residue was purified through silica gel column chromatography (ethyl acetate/methanol=95/5)to obtain a mixture of the entitled compound and an olefin-unreduced compound (2/1) (499 mg).

後処理

  1. concentrationThe reaction solution was concentrated under reduced pressure
  2. customthe resulting residue was purified through silica gel column chromatography (ethyl acetate/methanol=95/5)to
  3. customobtain
  4. additiona mixture of the entitled compound

出典と根拠

ORDレコード
ord-2e8e36378fc94ffc8d65a6a9eec7bda1
出典データセット
uspto-grants-2009_07
特許番号
US07566781B2

関連ノート

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