Bromine → 2-Hexyl-2-cyclopenten-1-one
反応式
[CH:1](=[C:7]1[CH2:11][CH2:10][CH2:9][C:8]1=[O:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].BrBr>>[CH2:1]([C:7]1[C:8](=[O:12])[CH2:9][CH2:10][CH:11]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]参加物
3
実験手順
In a 50 ml three-neck flask fitted with a thermometer, a condenser and a stirrer were placed 2-hexylidenecyclopentanone (15 g) synthesized in Reference Example 5 and bromine (0.03 g), followed by 6 hours of the reaction at 100-120° C. The crude product was purified by column chromatography (hexane/ethyl acetate: 95/5) to obtain 12.5 g of 2-hexyl-2-cyclopentenone (GC purity: 98.5%).
後処理
- customIn a 50 ml three-neck flask fitted with a thermometer, a condenser and a stirrer
- customfollowed by 6 hours of the reaction at 100-120° C
- customThe crude product was purified by column chromatography (hexane/ethyl acetate: 95/5)
出典と根拠
- ORDレコード
- ord-6893ba2d4bad43319e96b1054b3f8c59
- 出典データセット
- uspto-grants-2004_12
- 特許番号
- US06833481B2
反応ノート
読み込み中…