(2-Hydroxyphenyl)acetic acid → 2-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl ester

HRID 23082

反応式

HRID 23082 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][C:9]([OH:11])=O.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[OH:1])[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

参加物

3

反応物 2

HCID 11970(2-Hydroxyphenyl)acetic acidHCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 537176952-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl ester

実験手順

Following General Procedure BI above and using 2-hydroxyphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-c01da2a578f046fea35924a7d62e99c1
出典データセット
uspto-grants-2005_02
特許番号
US06849650B2

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