2,4-Dichlorophenylacetic acid → 2-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

HRID 23084

反応式

HRID 23084 の反応式
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10]([OH:12])=O.[NH2:13][CH:14]([CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH:19]([CH3:21])[CH3:20])=[O:16]>>[CH2:18]([O:17][C:15](=[O:16])[CH:14]([NH:13][C:10](=[O:12])[CH2:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[Cl:1])[CH2:22][CH3:23])[CH:19]([CH3:20])[CH3:21]

参加物

3

反応物 2

HCID 882092,4-Dichlorophenylacetic acidHCID 13743360Isobutyl 2-aminobutyrate

生成物 1

HCID 541261332-[(2,4-Dichlorophenyl)acetamido]butyric acid isobutyl ester

実験手順

Following General Procedure BI above and using 2,4-dichlorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

後処理

  1. customThe reaction was monitored by tlc on silica gel and purification
  2. filtrationwas by filtration

出典と根拠

ORDレコード
ord-8ad349b385cf40328f6910c801bc99ed
出典データセット
uspto-grants-2005_02
特許番号
US06849650B2

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