Sodium Methoxide → (5-Methoxy-biphenyl-3-yl)-thiourea
反応式
C([NH:9][C:10]([NH:12][C:13]1[CH:14]=[C:15]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:16]=[C:17]([O:19][CH3:20])[CH:18]=1)=[S:11])(=O)C1C=CC=CC=1.C[O-].[Na+]>CO>[CH3:20][O:19][C:17]1[CH:18]=[C:13]([NH:12][C:10]([NH2:9])=[S:11])[CH:14]=[C:15]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:16]=1参加物
4
実験手順
1-Benzoyl-3-(5-methoxy-biphenyl-3-yl)-thiourea (183 mg, 0.51 mmol) in methanol (5 ml) are treated with sodium methoxide (5.4M in methanol, 0.14 ml) and the formed precipitate is filtered off. Washing with methanol yields the product (115 mg, 88%) as off-white powder. MS: m/e=258 (M+).
後処理
- filtrationthe formed precipitate is filtered off
- washWashing with methanol
出典と根拠
- ORDレコード
- ord-1da8584fab624b88867a2bcf25ae0559
- 出典データセット
- uspto-grants-2004_12
- 特許番号
- US06835732B2
反応ノート
読み込み中…