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HRID 230869作成日:2026年10月26日

Water → 1-[2-(Benzyloxy)-6-hydroxyphenyl]ethan-1-one

https://huagongshe.com/reaction/230869

反応式

関与物質

役割名称HCID仕込み量
反応物WaterHCID 962—
反応物Benzyl BromideHCID 7498—
反応物Potassium CarbonateHCID 11430—
反応物2',6'-DihydroxyacetophenoneHCID 69687—
溶媒AcetoneHCID 180—
生成物1-[2-(Benzyloxy)-6-hydroxyphenyl]ethan-1-oneHCID 2775187—

反応手順

To a mixture of 2′,6′-dihydroxyacetophenone (4 g) and potassium carbonate (3.82 g) in acetone (40 mL) was added benzyl bromide (3.13 mL), and the mixture was stirred at room temperature overnight. The reaction mixture was poured into water, and the precipitated crystals were collected by filtration. The crystals were washed with water and n-hexane, and dried under reduced pressure to give the title compound (3.67 g).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07566699B2
出典データセットuspto-grants-2009_07
ORD IDord-ad510b46ab0447c5abe0f9bfcbc6058e
出典メモuspto-grants-2009_07