Water → 6'-Hydroxy-2'-(methoxycarbonylmethoxy)acetophenone
反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([OH:8])[C:3]=1[C:9](=[O:11])[CH3:10].C(=O)([O-])[O-].[K+].[K+].Br[CH2:19][C:20]([O:22][CH3:23])=[O:21].O>CC(C)=O>[OH:1][C:2]1[C:3]([C:9](=[O:11])[CH3:10])=[C:4]([O:8][CH2:19][C:20]([O:22][CH3:23])=[O:21])[CH:5]=[CH:6][CH:7]=1参加物
6
実験手順
To a mixture of 2′,6′-dihydroxyacetophenone (6 g) and potassium carbonate (5.72 g) in acetone (20 mL) was added methyl bromoacetate (3.73 mL), and the mixture was stirred at room temperature for 5 days. To the reaction mixture was added water, and the precipitated crystals were collected by filtration. The crystals were washed with water and dried under reduced pressure to give the title compound (7.89 g).
後処理
- filtrationthe precipitated crystals were collected by filtration
- washThe crystals were washed with water
- customdried under reduced pressure
出典と根拠
- ORDレコード
- ord-9697439f8c5f4eaf8fdafdd370708a5d
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07566699B2
反応ノート
読み込み中…