化工社化工社 化学情報印刷レポート · 研究参考用
Water → 1-(4-Methoxy-3,5-dimethylphenyl)propan-1-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Propionyl chloride | HCID 62324 | — |
| 反応物 | 2,6-Dimethylanisole | HCID 66088 | — |
| 反応物 | Aluminum(III) Chloride | HCID 6451240 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 1-(4-Methoxy-3,5-dimethylphenyl)propan-1-one | HCID 12963418 | 97.4% |
反応手順
13.6 g of 2,6-dimethylanisole was dissolved in 30 ml of methylene chloride, and 16 g of anhydrous aluminum chloride was added. Then, with water cooling, 11 g of propionyl chloride was added dropwise. The mixture was stirred at room temperature for 1 hour. The reaction mixture was poured into ice water, and the organic layer was separated and washed with water. The solvent was evaporated to give 18.7 g of 2,6-dimethyl-4-propionylanisole.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04695581 |
| 出典データセット | uspto-grants-1987_09 |
| ORD ID | ord-a533f31cbc8c4e4e951885f11f150b1e |
| 出典メモ | uspto-grants-1987_09 |