Hydrochloric Acid → (4,6-Dimethylpyrimidin-2-yl)cyanamide
反応式
[C:1]([NH:3][C:4]([NH2:6])=[NH:5])#[N:2].[CH3:7][C:8](=O)[CH2:9][C:10](=O)[CH3:11].Cl>O>[C:1]([NH:3][C:4]1[N:6]=[C:10]([CH3:11])[CH:9]=[C:8]([CH3:7])[N:5]=1)#[N:2]参加物
5
反応条件
- 温度
- 120 °C
実験手順
A mixture of 42 g (0.5 mol) of cyanoguanidine ("dicyanodiamide") and 50 g (0.5 mol) of 2,4-pentanedione ("acetylacetone") is heated to 120° C. for 15 hours. The reaction mixture is then cooled, after which 500 ml of water are added and the solution is acidified with hydrochloric acid at 0° C. to 10° C. The product obtained in crystalline form during this procedure is isolated by filtering it off under suction. 51.8 g (70% of theory) of 2-cyanoamino-4,6-dimethyl-pyrimidine of melting point 205° C. are obtained.
後処理
- temperatureThe reaction mixture is then cooled
- customThe product obtained in crystalline form during this procedure
- customis isolated
- filtrationby filtering it off under suction
出典と根拠
- ORDレコード
- ord-51595aaaff7745dbb35de9db42182aa9
- 出典データセット
- uspto-grants-1989_07
- 特許番号
- US04844730
反応ノート
読み込み中…