4-Carbobenzoxyoxybenzoic acid 1-methylbutyl ester → Pentan-2-YL 4-hydroxybenzoate
反応式
[CH3:1][CH:2]([O:6][C:7](=[O:25])[C:8]1[CH:13]=[CH:12][C:11]([O:14]C(OCC2C=CC=CC=2)=O)=[CH:10][CH:9]=1)[CH2:3][CH2:4][CH3:5].[H][H]>C(OCC)(=O)C.[C].[Pd]>[CH3:1][CH:2]([O:6][C:7](=[O:25])[C:8]1[CH:9]=[CH:10][C:11]([OH:14])=[CH:12][CH:13]=1)[CH2:3][CH2:4][CH3:5]参加物
5
実験手順
A solution of 10 m moles of the above 4-carbobenzoxyoxybenzoic acid 1-methylbutyl ester, 0.5 g of palladium carbon (5% catalyst) in 40 ml of ethyl acetate was reacted for four hours in an atmosphere of hydrogen gas. After the reaction, palladium carbon was filtered out using a membrane filter, and the filtrate was concentrated and purified by column chromatography to obtain 1.9 g of 4-hydroxybenzoic acid 1-methylbutyl ester. (yield: 89%)
後処理
- filtrationwas filtered out
- filtrationfilter
- concentrationthe filtrate was concentrated
- custompurified by column chromatography
出典と根拠
- ORDレコード
- ord-98774643b5724ebf8331924e0ee59645
- 出典データセット
- uspto-grants-1989_07
- 特許番号
- US04844835
反応ノート
読み込み中…