化工社化工社 化学情報印刷レポート · 研究参考用
4-Hydroxybenzoic Acid → 4-(1-Methylheptyloxycarbonyl)phenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | (R)-2-Octanol | HCID 80080 | — |
| 溶媒 | Benzene | HCID 241 | — |
| 生成物 | 4-(1-Methylheptyloxycarbonyl)phenol | HCID 11010379 | 43% |
反応手順
27.6 g of p-hydroxybenzoic acid and 39.0 g of (R)-2-octanol were refluxed for 10 hours in 300 ml of benzene in the presence of 0.5 ml of conc. sulfuric acid. Then, the reaction solution was cooled to the room temperature, and then concentrated and purified by column chromatography, to obtain 21.5 g of p-hydroxybenzoic acid 1-methylheptyl ester. (yield: 43%)
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04844835 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-9a63337d10b54f90af339903302db2f4 |
| 出典メモ | uspto-grants-1989_07 |