Hydrochloric Acid → 2-Amino-5-methoxybenzene-1-thiol

HRID 231054

反応式

HRID 231054 の反応式
[OH-].[K+].NC1[S:5][C:6]2[CH:12]=[C:11]([O:13][CH3:14])[CH:10]=[CH:9][C:7]=2[N:8]=1.Cl>C(O)(=O)C>[NH2:8][C:7]1[CH:9]=[CH:10][C:11]([O:13][CH3:14])=[CH:12][C:6]=1[SH:5]

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14797Potassium HydroxideHCID 156302-Amino-6-methoxybenzothiazole

生成物 1

HCID 2355092-Amino-5-methoxybenzene-1-thiol

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒

実験手順

To a stirred solution of 8N potassium hydroxide (1.3 1) was added 2-amino-6-methoxybenzothiazole (750 g) and the mixture was refluxed overnight. The resulting solution was neutralized by the addition of conc. HCl to pH 8.0, then acetic acid to pH 6.0. The precipitate which formed was filtered and washed with water to afford the title compound which was used immediately in Step 3.

後処理

  1. temperaturethe mixture was refluxed overnight
  2. customThe precipitate which formed
  3. filtrationwas filtered
  4. washwashed with water

出典と根拠

ORDレコード
ord-2cd057767225428ea19ca870db47e56a
出典データセット
uspto-grants-1989_07
特許番号
US04845083

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