関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 4,4'-Dichlorobenzhydryl chloride | HCID 13078 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | HCID 178418936 | HCID 178418936 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 1-[bis(4-chlorophenyl)methyl]-1H-1,2,3-triazole | HCID 14390654 | — |
| 生成物 | 2-[bis(4-chlorophenyl)methyl]-2H-1,2,3-triazole | HCID 20034902 | — |
反応手順
Following the general procedure of Example 1B, 5.0 g of 1,2,3-triazole in 100 ml fo dimethylformamide were treated first with 1.44 g of sodium hydride (60% in mineral oil), and then with 5.0 g of 4.4'-dichlorobenzhydryl chloride. The reactants were stirred overnight at about 25° C. and then heated for 1 hour on a steam bath. Chromatography of the residue after work-up provided 2.4 g of the undesired 2-[bis(4-chlorophenyl)methyl]-2H-1,2,3-triazole and 3.1 g of the desired title product, m.p. 124°-125° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04845227 |
|---|
| 出典データセット | uspto-grants-1989_07 |
|---|
| ORD ID | ord-809019cea303426b8bafa091cd2074d2 |
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| 出典メモ | uspto-grants-1989_07 |
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