Sodium hydroxide ethanol → Sodium butyl glycidyl phosphate

HRID 231284

反応式

HRID 231284 の反応式
[P:1]([O-:14])([O:8][CH2:9][CH:10]([OH:13])[CH2:11]Cl)([O:3][CH2:4][CH2:5][CH2:6][CH3:7])=[O:2].[Na+:15].C(O)C.[OH-].[Na+]>C(O)C>[P:1]([O-:14])([O:8][CH2:9][CH:10]1[O:13][CH2:11]1)([O:3][CH2:4][CH2:5][CH2:6][CH3:7])=[O:2].[Na+:15]

参加物

4

反応物 2

HCID 23692425Sodium hydroxide ethanolHCID 86743212HCID 86743212、化合物

生成物 1

HCID 23698436Sodium butyl glycidyl phosphate収率 100%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

反応条件

温度
70 °C

実験手順

50 g (0.19 mol) of sodium butyl 2-hydroxy-3chloropropyl phosphate was charged into a reactor, to which 1000 ml of ethanol was added, followed by agitation and heating to 70° C. to obtain a uniform mixture. Thereafter, the reaction system was cooled down to room temperature, to which was gradually added 88.6 g (0.19 mol) of a 0.0021 mol/g sodium hydroxide ethanol solution, followed by agitation for 3 hours while keeping the temperature. The HPLC analysis revealed the disappearance of a peak of the starting material with a peak for the resultant new product appearing. The resultant NaCl precipitate was removed by filtration and the ethanol was distilled off under reduced pressure to obtain 43 g (yield: 100%) of sodium butyl glycidyl phosphate.

後処理

  1. additionwas added
  2. customto obtain a uniform mixture
  3. temperatureThereafter, the reaction system was cooled down to room temperature, to which
  4. customThe resultant NaCl precipitate was removed by filtration
  5. distillationthe ethanol was distilled off under reduced pressure

出典と根拠

ORDレコード
ord-e17e630651bc4823b01a22b74fce5162
出典データセット
uspto-grants-1989_07
特許番号
US04845239

関連ノート

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