関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dichloromethane | HCID 6344 | — |
| 反応物 | 10-Undecen-1-ol | HCID 8185 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 触媒 | Pyridine | HCID 1049 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 11-Chloro-1-undecene | HCID 543805 | 84.7% |
反応手順
To a solution of 100 g (0.588 mole) of 10-undecenyl alcohol and 2 g of pyridine was added 75 g (0.63 mole) of SOCl2 dropwise over a period of 45 minutes at 25° C. The solution was heated at 65° C. for 5 hours. CH2Cl2 (100 mL) was added and the solution was water washed twice, dried with MgSO4, filtered, and the CH2Cl2 evaporated. The residue (103 g) by GC analysis showed a purity of 99.3% VIII with 0.7% alcohol; IR showed no OH band and absorbence at 1641-1. Distillation (15.24 centimeter jacketed Vigreaux column) gave 94 g VIII (bp 104°-105° C. at 6 mm) (GC showed no alcohol; 100% VIII).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US04845271 |
|---|
| 出典データセット | uspto-grants-1989_07 |
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| ORD ID | ord-5d598318549b483b9d8cee0ddc53e0bd |
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| 出典メモ | uspto-grants-1989_07 |
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