Ammonia → HCID 20071066、化合物

HRID 231375ノート

反応式

HRID 231375 の反応式
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:9][CH3:10])[C:3]=1[N+:11]([O-:13])=[O:12].[NH3:14]>O.C(O)C>[Cl:8][C:6]1[CH:5]=[C:4]([NH:9][CH3:10])[C:3]([N+:11]([O-:13])=[O:12])=[C:2]([NH2:14])[CH:7]=1

参加物

5

反応物 2

HCID 222AmmoniaHCID 20071071HCID 20071071、化合物

生成物 1

HCID 20071066HCID 20071066、化合物

試薬・触媒・溶媒 2

HCID 702Ethanol溶媒HCID 962Water溶媒

実験手順

0.034 mole (7.5 g) of 2,4-dichloro-6-methylaminonitrobenzene is added to 100 ml of a 28% solution of ammonia in water and 50 ml of ethanol in an autoclave. The reaction medium is heated for 12 hours at 145°-150° C., the pressure being 12 kg/cm2. The product expected precipitates from the reaction medium on cooling. After draining and re-impasting in water, it is dried by heating under vacuum in the presence of phosphorous pentoxide. Recrystallized from isopropanol, it melts at 129° C.

後処理

  1. temperatureThe reaction medium is heated for 12 hours at 145°-150° C.
  2. customThe product expected precipitates from the reaction medium
  3. temperatureon cooling
  4. customit is dried
  5. temperatureby heating under vacuum in the presence of phosphorous pentoxide
  6. customRecrystallized from isopropanol, it melts at 129° C.

出典と根拠

ORDレコード
ord-a4fe7d87c5e74771a36a028cfe2c8f13
出典データセット
uspto-grants-1989_07
特許番号
US04845293

反応ノート

読み込み中…