化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Dichloro-2-nitrobenzene → 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Dichloro-2-nitrobenzene | HCID 11759 | — |
| 反応物 | 3-Amino-1,2-propanediol | HCID 73561 | — |
| 溶媒 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 生成物 | 2-(beta,gamma-Dihydroxypropyl)amino-6-chloronitrobenzene | HCID 20035240 | — |
反応手順
0.2 mole (38.4 g) of 2,6-dichloronitrobenzene and 0.6 mole (54.6 g) of 3-aminopropane-1,2-diol in 200 ml of 1-methyl-2-pyrrolidone are heated to 80° C. The reaction mixture is diluted with ice. The product expected precipitates. After recrystallizing from isopropanol, it melts at 126° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04845293 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-15b4c36b60604eb984e0b22c2aa363ea |
| 出典メモ | uspto-grants-1989_07 |