化工社化工社 化学情報印刷レポート · 研究参考用
Tetramethoxypropane → Ethyl pyrazolo(1,5-a)pyrimidine-3-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Tetramethoxypropane | HCID 66019 | — |
| 反応物 | ethyl 3-amino-1H-pyrazole-4-carboxylate | HCID 81472 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | Ethyl pyrazolo(1,5-a)pyrimidine-3-carboxylate | HCID 7021267 | 58.2% |
反応手順
A stirred mixture of 10.88 g of 5-amino-4-pyrazolecarboxylic acid, ethyl ester, 11.51 g of malonaldehyde bis(dimethyl acetal) and 100 ml of glacial acetic acid was heated at reflux for 16 hours, then worked up as described in Example 50 to give 7.8 g of pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, ethyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04847256 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-5f8b8cdbe5c44c21aa1db52de5971b43 |
| 出典メモ | uspto-grants-1989_07 |