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Water → 2,6-Bis(1,1-dimethylethyl)-4-(methylthio)phenol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Triethyl phosphite | HCID 31215 | — |
| 反応物 | 2,6-DI-Tert-butyl-4-thiocyanato-phenol | HCID 619245 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 2,6-Bis(1,1-dimethylethyl)-4-(methylthio)phenol | HCID 14479952 | — |
反応手順
A mixture of 3,5-bis(1,1-dimethylethyl)-4-hydroxyphenylthiocyanate (238 g, 0.90 mole), triethylphosphite (225 g, 1.35 mole), water (200 g), and methanol (2000 ml) was stirred at reflux for two hours. Upon cooling, the mixture was concentrated in vacuo. The residue was triturated with water, and the solid was collected by filtration and air dried. Recrystallization from aqueous methanol gave the title compound, m.p. 69°-71°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04847305 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-eb54f59a4b2e411eb36221891cf989dc |
| 出典メモ | uspto-grants-1989_07 |