化工社化工社 化学情報印刷レポート · 研究参考用
1,3-Difluorobenzene → 1,2-Difluorobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1,3-Difluorobenzene | HCID 9741 | — |
| 反応物 | Fluorobenzene | HCID 10008 | — |
| 反応物 | Fluorine | HCID 24524 | — |
| 生成物 | 1,2-Difluorobenzene | HCID 9706 | — |
| 生成物 | Fluorobenzene | HCID 10008 | — |
反応手順
According to Sams et al, "Molecular Sieve Fluorination of Fluorobenzene Using Elemental Fluorine," J. Org. Chem. 43(11), 2273 (1978), attempts were made to prepare 1,3-difluorobenzene using a molecular sieve fluorination technique. Fluorination of monofluorobenzene resulted in the isolation of various isomers of difluorobenzene in 19% yield; the highest reported yield for the meta isomer was 1.2%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04847442 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-94ebc396e22e452ca94dedae374927e1 |
| 出典メモ | uspto-grants-1989_07 |