関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Barium Sulfate | HCID 24414 | — |
| 反応物 | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Decalin | HCID 7044 | — |
| 生成物 | 2,4-Difluorobenzaldehyde | HCID 73770 | — |
反応手順
30 ml (27 g) of decahydronaphthalene and 0.5 g (2.3×10-4 ml) of a catalyst of 5% palladium on a barium sulfate support were added to the flask containing the 2,4-difluorobenzoylchloride. The reaction was purged with H2 for 0.25 hour, then the temperature was raised to 130° C. Hydrogen was dispersed through the system for 6 hours. The product 2,4-difluorobenzaldehyde was isolated as a colorless liquid. Yield 9.8 g (82%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04847442 |
|---|
| 出典データセット | uspto-grants-1989_07 |
|---|
| ORD ID | ord-75dc8a895d0348e8b51de7c7dc829a70 |
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| 出典メモ | uspto-grants-1989_07 |
|---|
