化工社化工社 化学情報印刷レポート · 研究参考用
N-bromobutanimide → Methyl 2-bromo-2-(4-chlorophenyl)acetate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | Methyl 4-chlorophenylacetate | HCID 104196 | — |
| 溶媒 | Carbon Tetrachloride | HCID 5943 | — |
| 生成物 | Methyl 2-bromo-2-(4-chlorophenyl)acetate | HCID 10777987 | 103.5% |
反応手順
To a solution of 102 g (0.55 mole) of methyl (4-chlorophenyl)acetate in 100 ml of carbon tetrachloride was added 97.9 g (0.55 mole) of N-bromosuccinimide. The resulting mixture was refluxed and irradiated with a 500 W bromo lamp for 5 hours. It was then cooled, filtered, and the filtrate was evaporated to dryness to give 150 g (103% yield) of methyl (4-chlorophenyl)bromoacetate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04849434 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-3293487a67ca4be8bcc533901b7811be |
| 出典メモ | uspto-grants-1989_07 |