Hydrochloric Acid → HCID 14233599、化合物
反応式
[NH2:1][C:2]1[CH:12]=[C:11]([Br:13])[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].C(O)C.[ClH:17]>C(OCC)C>[ClH:17].[NH2:1][C:2]1[CH:12]=[C:11]([Br:13])[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5]参加物
5
実験手順
At room temperature, a solution of 3.09 g (0.0127 mol) of ethyl 2-amino-4-bromobenzoate and 30 ml absolute ethanol was saturated with dry hydrogen chloride gas. A colorless precipitate formed in the warm solution. When it was again at room temperature, the solution was diluted with 30 ml of diethyl ether; the resulting crystalline product was filtered and washed with diethyl ether. Thus there was obtained 2.72 g (77%) of the title compound: m.p. 147°-150° C. Analysis calculated for C9H11BrClNO2 : C, 38.53; H, 3.95; N, 4.99%. Found: C, 38.48; H; 4.02; N, 4.99%.
後処理
- customAt room temperature
- customA colorless precipitate formed in the warm solution
- customwas again at room temperature
- filtrationthe resulting crystalline product was filtered
- washwashed with diethyl ether
出典と根拠
- ORDレコード
- ord-a294c371671d4cf2baf9a4720ebcedff
- 出典データセット
- uspto-grants-1989_07
- 特許番号
- US04849518
反応ノート
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