関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | 2-(3-Ethynylphenyl)-1,3-dioxolane | HCID 19897393 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 3-Ethynylbenzaldehyde | HCID 2771644 | 87.8% |
反応手順
A multinecked, round bottom flask fitted with a mechanical stirrer, reflux condenser and thermometer, was charged 50.4 g (0.289 mol) of the product of Example XI, 400 ml of distilled water and 1 g of concentrated hydrochloric acid. The mixture was heated to 60° C. and maintained at that temperature for about 4 hours and then cooled to room temperature which yielded the product as a yellow precipitate. The product was filtered, washed with distilled water and allowed to dry on the funnel overnight to yield 33 g (0.254 mol, 87.8% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US04849546 |
|---|
| 出典データセット | uspto-grants-1989_07 |
|---|
| ORD ID | ord-492320e4c9fb4419bbe58ef8f3ea0518 |
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| 出典メモ | uspto-grants-1989_07 |
|---|
