化工社化工社 化学情報印刷レポート · 研究参考用
4-tert-Butylcyclohexanone → Cyclohexane, 1-(1,1-dimethylethyl)-4-methylene-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-tert-Butylcyclohexanone | HCID 7392 | — |
| 反応物 | Tetrahydrofuran | HCID 8028 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 溶媒 | Hexane | HCID 8058 | — |
| 生成物 | Cyclohexane, 1-(1,1-dimethylethyl)-4-methylene- | HCID 139425 | 70% |
反応手順
BDAM (3.00 grams) was suspended in 40 milliliters of methylene chloride and 2 molar equivalents of THF were added at 0° C. After a homogeneous solution was formed, 1 molar equivalent of TEAL in 10 milliliters of hexane was added followed by 2.20 grams of 4-tert-butylcyclohexanone. After overnight stirring, reaction mixture was hydrolyzed and worked up as described in Example 1. A total of 1.50 grams of 4-tert-butyl-1-methylenecyclohexane was isolated (70% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04849574 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-e97d4a423c634dc3b47fab2cc27e75c0 |
| 出典メモ | uspto-grants-1989_07 |