化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2,4-Dichloro-5-fluoro-3-nitrobenzoic acid | HCID 2734259 | — |
| 触媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | Benzoyl chloride, 2,4-dichloro-5-fluoro-3-nitro- | HCID 11818130 | — |
反応手順
254 g (1 mol) of 2,4-dichloro-5-fluoro-3-nitrobenzoic acid are refluxed in 700 ml of thionyl chloride with addition of 3 drops of dimethylformamide until the gas evolution ceases. Excess thionyl chloride is removed by distillation, and the residue is fractionated in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04851160 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-7393af94a2b148a98950d68bf3c02574 |
| 出典メモ | uspto-grants-1989_07 |