Azane;hydrate → HCID 20030947、化合物

反応式

[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH:16]([C:17](OC)=[O:18])[O:15][NH:14][C:13]1=[O:21])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.O.[NH3:23]>>[CH2:1]([O:8][C:9]([NH:11][CH:12]1[CH:16]([C:17](=[O:18])[NH2:23])[O:15][NH:14][C:13]1=[O:21])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

反応物 2

HCID 12896473Azane;hydrate

HCID 20030921HCID 20030921、化合物

生成物 1

HCID 20030947HCID 20030947、化合物

実験手順

In 2.4 ml of concentrated ammonia water was dissolved 150 mg of 4-benzyloxycarbonylamino-5-methoxycarbonyl-3-isoxazolidinone (mixture of 4,5-cis compound and -trans compound). The solution was left standing at room temperature for 20 minutes, which was concentrated to dryness under reduced pressure. Ether was added to the concentrate to give 138 mg of 4-benzyloxycarbonylamino-5-carbamoyl-3-isoxazolidinone as crystals.

後処理

waitThe solution was left
concentrationwhich was concentrated to dryness under reduced pressure
additionEther was added to the
concentrationconcentrate

出典と根拠

ORDレコード: ord-eee281fc6c844eb4bdc5aa560c1c873c
出典データセット: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04851422

反応ノート

読み込み中…

参加物