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Methanol → 4-[[2-(3,4,5-Trimethoxyphenyl)ethyl](methyl)amino]hexan-3-ol
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 2,3-Diethyloxirane | HCID 138264 | — |
| 反応物 | N-Methylmescaline | HCID 138365 | — |
| 生成物 | 4-[[2-(3,4,5-Trimethoxyphenyl)ethyl](methyl)amino]hexan-3-ol | HCID 20031381 | — |
反応手順
Combine 22.5 g (0.1 mol) of N-methyl-3,4,5-trimethoxybenzeneethanamine and 10 g (0.1 mol) of 2,3-diethyloxirane in 150 mL of 90% aqueous methanol. Heat the reaction at 50° C. and follow the progress of the reaction by thin-layer chromatography. At the completion of the reaction remove the solvent in vacuo and chromatograph the residue on silica gel to obtain the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04851526 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-9557d6b1d5794e29856206cf104fc55c |
| 出典メモ | uspto-grants-1989_07 |