化工社化工社 化学情報印刷レポート · 研究参考用
Bromine → 2-Bromo-1-[4-(1H-imidazol-1-yl)phenyl]ethanone hydrobromide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 1-(4-(1H-Imidazol-1-yl)phenyl)ethanone | HCID 82316 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Hydrogen Bromide | HCID 260 | — |
| 生成物 | 2-Bromo-1-[4-(1H-imidazol-1-yl)phenyl]ethanone hydrobromide | HCID 20031310 | — |
反応手順
Add bromine (5.71 mL, 0.111 mol) to a solution of 4'-(1H-imidazol-1-yl)acetophenone (20.75 g, 0.111 mol) in 30-32% HBr in acetic acid. Stir the mixture overnight and collect the crystals. Wash the crystals with ethanol (3×50 mL) and air dry for 2h at room temperature to afford the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04851526 |
| 出典データセット | uspto-grants-1989_07 |
| ORD ID | ord-27f1074a998940f2a6cf78bb3d89b3ee |
| 出典メモ | uspto-grants-1989_07 |