1-Hydroxybenzotriazole → ethyl 2-[4-[(4-chloro-5-ethyl-1H-imidazole-2-carbonyl)amino]-3-ethoxypiperidin-1-yl]-4-(1-methoxyethylcarbamoyl)-1,3-thiazole-5-carboxylate

反応式

[CH3:34][O:35][CH:36]([CH3:37])[NH2:38].[Cl:1][c:2]1[n:3][c:4]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:31][CH2:32][CH3:33])[CH2:14][N:15]([c:18]3[s:19][c:20]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[c:21]([C:23](=[O:24])[OH:25])[n:22]3)[CH2:16][CH2:17]2)[nH:5][c:6]1[CH2:7][CH3:8].[OH:39][n:40]1[c:41]2[c:42]([cH:43][cH:44][cH:45][cH:46]2)[n:47][n:48]1>>[Cl:1][c:2]1[n:3][c:4]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:31][CH2:32][CH3:33])[CH2:14][N:15]([c:18]3[s:19][c:20]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[c:21]([C:23](=[O:25])[NH:38][CH:36]([O:35][CH3:34])[CH3:37])[n:22]3)[CH2:16][CH2:17]2)[nH:5][c:6]1[CH2:7][CH3:8]