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HRID 232352作成日：2026年10月26日

2-(2,4-Dichlorophenoxy)propanoyl chloride → 5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine

https://huagongshe.com/reaction/232352

反応式

関与物質

役割名称HCID仕込み量
反応物2-(2,4-Dichlorophenoxy)propanoyl chlorideHCID 14303380—
反応物5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridineHCID 18633458—
生成物5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridineHCID 18633419—

反応手順

In an analogous manner, from 2(RS)-(2,4-dichlorophenoxy)propionyl chloride (prepared from the acid) and 5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine, there was obtained 5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine of melting point 121°-124° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US04851519
出典データセットuspto-grants-1989_07
ORD IDord-5115850a93e645e7930f3b47c7e7e64a
出典メモuspto-grants-1989_07