Acetic Anhydride → 2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione
反応式
[O:1]=[C:2]1[NH:7][C:6](=[O:8])[CH:5]=[N:4][NH:3]1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>>[C:9]([N:3]1[C:2](=[O:1])[NH:7][C:6](=[O:8])[CH:5]=[N:4]1)(=[O:11])[CH3:10]参加物
3
反応条件
- 温度
- 0 °C
実験手順
3,5-dioxo-(2H,4H)-1,2,4-triazine (48.88 g) is heated under reflux of acetic anhydride (300 ml) for 90 minutes. After cooling and concentration to dryness under vacuum, the residue is taken up in toluene (300 ml) and cooled at 0° C. for 2 hours. The white precipitate which forms is filtered off, centrifuged, and dried under vacuum at 70° C. so as to give the compound 11a (57.6 g).
後処理
- temperatureAfter cooling
- concentrationconcentration to dryness under vacuum
- filtrationThe white precipitate which forms is filtered off
- customcentrifuged, and dried under vacuum at 70° C. so as
出典と根拠
- ORDレコード
- ord-f7c15039966a406e986f2d3e26834dd6
- 出典データセット
- uspto-grants-1997_01
- 特許番号
- US05591743
反応ノート
読み込み中…