4-tert-Butylbenzylamine → Tebufenpyrad

HRID 232720

反応式

HRID 232720 の反応式
[CH2:1]([NH:3][C:4]([C:6]1[N:10]([CH3:11])[N:9]=[C:8]([CH2:12][CH3:13])[C:7]=1[Cl:14])=[O:5])[CH3:2].[C:15]([C:19]1[CH:26]=[CH:25]C(CN)=[CH:21][CH:20]=1)([CH3:18])([CH3:17])[CH3:16]>>[C:15]([C:19]1[CH:26]=[CH:25][C:2]([CH2:1][NH:3][C:4]([C:6]2[N:10]([CH3:11])[N:9]=[C:8]([CH2:12][CH3:13])[C:7]=2[Cl:14])=[O:5])=[CH:21][CH:20]=1)([CH3:18])([CH3:17])[CH3:16]

参加物

3

反応物 2

HCID 27356554-tert-ButylbenzylamineHCID 54498586Ethyl 4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide

生成物 1

HCID 86354Tebufenpyrad

反応条件

温度
200 °C

実験手順

A mixture of ethyl 4-chloro-3-ethyl-1-methylpyrazole-5-carboxamide and 4-tert-butylbenzylamine is heated to 200° C. for four hours with continuous stirring. Thereafter the reaction mixture is cooled to room temperature and the reaction mixture purified by silica gel chromatography to obtain the desired product 115°-117° C.

後処理

  1. temperatureThereafter the reaction mixture is cooled to room temperature
  2. customthe reaction mixture purified by silica gel chromatography

出典と根拠

ORDレコード
ord-c599d53ad0804b5bbf9e2500d2967792
出典データセット
uspto-grants-1997_01
特許番号
US05591765

関連ノート

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