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Thiophene-3-sulfonyl Chloride → N-(4-bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thiophene-3-sulfonyl Chloride | HCID 2776378 | — |
| 反応物 | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| 生成物 | N-(4-bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide | HCID 12146375 | 22% |
反応手順
N-(4-Bromo-3-methyl-5-isoxazolyl)thiophene-3-sulfonamide was prepared in the same manner as described in Example 2 from thiophene-3-sulfonyl chloride with 5-amino-4-bromo-3-methylisoxazole in 22% yield. Purification by column chromatography using 10% MeOH/CHCl3 as eluent gave a pale brown oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05591761 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-5648f23a8a5649a0a6503bd53864150c |
| 出典メモ | uspto-grants-1997_01 |