Methyl (2-aminoindan-5-yl)acetate hydrochloride → 2-Aminoindane-5-acetic acid hydrochloride

HRID 232820ノート

反応式

HRID 232820 の反応式
[ClH:1].[NH2:2][CH:3]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH2:12][C:13]([O:15]C)=[O:14])[CH:9]=2)[CH2:4]1>Cl>[ClH:1].[NH2:2][CH:3]1[CH2:11][C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH2:12][C:13]([OH:15])=[O:14])[CH:9]=2)[CH2:4]1

参加物

3

反応物 1

HCID 23359670Methyl (2-aminoindan-5-yl)acetate hydrochloride

生成物 1

HCID 677154512-Aminoindane-5-acetic acid hydrochloride

試薬・触媒・溶媒 1

HCID 313Hydrochloric Acid溶媒

実験手順

3.6 g of methyl 2-aminoindane-5-acetatehydrochloride are refluxed for 3 hours in 160 ml of semiconcentrated hydrochloric acid. The hydrochloric acid is distilled off and the remaining product is triturated with a little ethanol, suction filtered and dried in vacuo.

後処理

  1. distillationThe hydrochloric acid is distilled off
  2. customthe remaining product is triturated with a little ethanol, suction
  3. filtrationfiltered
  4. customdried in vacuo

出典と根拠

ORDレコード
ord-9ad09ef9d76a46ef9b8d69b40e8a8f64
出典データセット
uspto-grants-1997_01
特許番号
US05591769

反応ノート

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