Ethyl 6-bromohexanoate → 11-(5-Carboxypentylthio)-2-(7-chloroquinolin-2-yl)methoxy-6,11-dihydrodibenz[b,e]oxepine
反応式
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH2:12][O:13][C:14]3[CH:29]=[CH:28][C:17]4[O:18][CH2:19][C:20]5[CH:27]=[CH:26][CH:25]=[CH:24][C:21]=5[CH:22]([SH:23])[C:16]=4[CH:15]=3)=[N:9]2)=[CH:4][CH:3]=1.Br[CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][C:36]([O:38]CC)=[O:37]>>[C:36]([CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][S:23][CH:22]1[C:21]2[CH:24]=[CH:25][CH:26]=[CH:27][C:20]=2[CH2:19][O:18][C:17]2[CH:28]=[CH:29][C:14]([O:13][CH2:12][C:8]3[CH:7]=[CH:6][C:5]4[C:10](=[CH:11][C:2]([Cl:1])=[CH:3][CH:4]=4)[N:9]=3)=[CH:15][C:16]1=2)([OH:38])=[O:37]参加物
3
実験手順
2-(7-Chloroquinolin-2-yl)methoxy-11-mercapto-6,11-dihydrodibenz[b,e]oxepine and ethyl 6-bromohexanoate were used and reacted in the same manner as in Example 24 to obtain the title compound.
後処理
- customreacted in the same manner as in Example 24
出典と根拠
- ORDレコード
- ord-c2463ddca61a458e8d30e76bf115cb1c
- 出典データセット
- uspto-grants-1997_01
- 特許番号
- US05591752
反応ノート
読み込み中…