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HRID 232898作成日:2026年10月26日

Sodium Hydroxide → 2-{4,6-bis-[4-(2-Ethylhexyloxy)phenyl]-s-triazin-2-yl}-5-(2-ethylhexyloxy)phenol

https://huagongshe.com/reaction/232898

反応式

関与物質

役割名称HCID仕込み量
反応物Sodium HydroxideHCID 14798—
反応物2-Ethylhexyl bromideHCID 86804—
反応物4-{4,6-Bis[4-(2-ethylhexyloxy)phenyl]-s-triazin-2-yl}-1,3-dihydroxybenzeneHCID 135563262—
溶媒2-MethoxyethanolHCID 8019—
生成物2-{4,6-bis-[4-(2-Ethylhexyloxy)phenyl]-s-triazin-2-yl}-5-(2-ethylhexyloxy)phenolHCID 135576265101.5%

反応手順

A 1 l sulfonating flask equipped with stirrer, condenser, internal thermometer and dropping funnel is charged at 80° C. with 83.7 g (0.14 mol) of 4-{4,6-bis[4-(2-ethylhexyloxy)phenyl]-s-triazin-2-yl}-1,3-dihydroxybenzene together with 500 ml of methylcellosolve. 18.1 g of 30% sodium hydroxide solution (0.16 mol) are added, stirring is continued for 15 minutes, and a solution of 31.4 g (0.16 mol) of 3-bromomethylheptane and 30 ml of methylcellosolve is then added dropwise over a period of 30 minutes. After 24 hours of stirring at 110° C., alkylation is complete (thin-layer chromatogram). The mixture is evaporated to dryness in vacuo, the residue is dissolved in 500 ml of toluene, the resulting solution is filtered, and the filtrate is extracted with water. The organic phase is dried over sodium sulfate and the solvent is distilled off to give 100.9 g of a red-brown oil. The crude product is dissolved in 200 ml of 97.5:2.5 toluene/ethyl acetate and purified by chromatographing it through silica gel (10 cm×40 cm). This gives 79.4 g (80% of theory) of the compound of the formula ##STR26## as a honey-like, red-brown resin.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US05591850
出典データセットuspto-grants-1997_01
ORD IDord-7a638ddd8026439b90a6abd90a91b00e
出典メモuspto-grants-1997_01