Formic Acid → 3-(Formylamino)benzoic acid

HRID 2332

反応式

HRID 2332 の反応式
[C:1](OC(=O)C)(=[O:3])C.C(O)=O.[NH2:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16]>O>[CH:1]([NH:11][C:12]1[CH:13]=[C:14]([CH:18]=[CH:19][CH:20]=1)[C:15]([OH:17])=[O:16])=[O:3]

参加物

5

反応物 3

HCID 284Formic AcidHCID 74193-Aminobenzoic AcidHCID 7918Acetic Anhydride

生成物 1

HCID 152489873-(Formylamino)benzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Acetic anhydride (76 ml) was added to 98% formic acid (130 ml) and the mixture stirred at r.t. 30 min, then 3-aminobenzoic acid (15 g, 109.5 mmol) added. The mixture was stirred at r.t. for 1 h, then water (1.3 L) added and stirring continued overnight. The resultant white precipitate was collected, washed with water and dried in vacuo over P2O5 (15.4 g, 85%).

後処理

  1. stirringThe mixture was stirred at r.t. for 1 h
  2. stirringstirring continued overnight
  3. customThe resultant white precipitate was collected
  4. washwashed with water
  5. dry with materialdried in vacuo over P2O5 (15.4 g, 85%)

出典と根拠

ORDレコード
ord-5570e335404a45e8bde112385306c6b2
出典データセット
uspto-grants-1998_03
特許番号
US05728829

関連ノート

読み込み中…