Sodium azide ammonium chloride → 5-[4-[3-(5-Methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-1,3-butadien-1-yl]tetrazole
反応式
[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:16]=[C:17](/[CH:21]=[CH:22]/[CH:23]=[CH:24]/[C:25]#[N:26])[CH:18]=[CH:19][CH:20]=1.[Cl-].[NH4+].[N-:29]=[N+:30]=[N-:31].[Na+]>>[CH3:1][C:2]1[O:6][C:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)=[N:4][C:3]=1[CH2:13][O:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=[CH:24][C:25]2[NH:31][N:30]=[N:29][N:26]=2)[CH:18]=[CH:19][CH:20]=1参加物
3
実験手順
According to the method described for Example 1, (E,E)-5-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-2,4-pentadienenitrile was allowed to react with sodium azide -ammonium chloride to give 5-[4-[3-(5-methyl-2-phenyl-4-oxazolylmethoxy)phenyl]-1,3-butadien-1-yl]tetrazole. Recrystallization from methanol gave colorless prisms, m.p.201°-202° C.
出典と根拠
- ORDレコード
- ord-e28effe824314dd78bf7e12d44d4cb56
- 出典データセット
- uspto-grants-1997_01
- 特許番号
- US05591862
反応ノート
読み込み中…