(+-)-Homocysteine → Captopril

HRID 233426

反応式

HRID 233426 の反応式
N[C@@H](CCC(N[C@H:11]([C:14]([NH:16][CH2:17][C:18]([OH:20])=[O:19])=[O:15])[CH2:12][SH:13])=O)C(O)=O.N[C@H:22]([C:25](O)=O)[CH2:23]S.N[CH:29](C(O)=O)CCS.CN(C1C=CC2N=C3C(=CC(C=C3)=[N+](C)C)SC=2C=1)C.C(N[C@H](C(O)=O)CS)(=O)C>>[CH3:29][C@@H:11]([C:14]([N:16]1[C@H:17]([C:18]([OH:20])=[O:19])[CH2:25][CH2:22][CH2:23]1)=[O:15])[CH2:12][SH:13]

参加物

6

実験手順

Glutathione, L-cysteine, DL-homocysteine, D-penicillin, hemoglobin Coovine), methylene blue and Medium 199 sets were purchased from Sigma Chemical Co., St. Louis, MO. N-acetylcysteine was obtained from Aldrich Chemical Co., Milwaukee, WI. Captopril was kindly provided by Dr. Victor Dzau. Sodium nitrite, histamine and methacholine were purchased from Fisher Scientific, Fairlawn,. N.J. Leukotriene D4 was purchased from Anaquest, BOC Inc., Madison, WI. Antibiotic/antimycotic mixture (10,000 U/ml penicillin G sodium, 10,000 mg/ml, streptomycin sulfate, 25 mg/ml amphotericin B) was purchased from Gibco laboratories, Grand Island, NY. Radioimmunoassay kits for the determination of cyclic GMP were purchased from New England Nuclear, Boston, MA.

出典と根拠

ORDレコード
ord-165c625bc2a84912824c9ea45207da50
出典データセット
uspto-grants-1997_01
特許番号
US05593876

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