Bromobenzene → 1,6-dimethyl-4-hydroxy-N-(5-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide

反応式

[Br:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[CH3:1][n:2]1[c:3](=[O:15])[c:4]([C:10]([O:12][CH2:11][CH3:13])=[O:14])[c:5]([OH:9])[cH:6][c:7]1[CH3:8].[NH2:16][c:17]1[s:18][c:19]([CH3:22])[cH:20][n:21]1>>[CH3:1][n:2]1[c:3](=[O:15])[c:4]([C:10](=[O:12])[NH:16][c:17]2[s:18][c:19]([CH3:22])[cH:20][n:21]2)[c:5]([OH:9])[cH:6][c:7]1[CH3:8]

参加物

反応物 3

HCID 7961Bromobenzene

HCID 3517702-Amino-5-methylthiazole

HCID 57619607Ethyl 1,6-dimethyl-4-hydroxy-2-oxo-1,2-dihydropyridine-3-carboxylate

生成物 1

HCID 576196381,6-dimethyl-4-hydroxy-N-(5-methylthiazol-2-yl)-2-oxo-1,2-dihydropyridine-3-carboxamide

出典と根拠

ORDレコード: ord-b314a9c40e7b4c7190130322d2d4b5da
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…