Hydrochloric Acid → 4,6-difluoro-N-((2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine

反応式

[Cl:2][CH2:3][c:4]1[c:5](-[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[cH:9][c:10]([CH3:13])[cH:11][cH:12]2.[ClH:1].[F:21][c:22]1[n:23][c:24]([NH2:29])[n:25][c:26]([F:28])[cH:27]1>>[CH2:3]([c:4]1[c:5](-[c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[cH:9][c:10]([CH3:13])[cH:11][cH:12]2)[NH:29][c:24]1[n:23][c:22]([F:21])[cH:27][c:26]([F:28])[n:25]1

参加物

反応物 3

HCID 313Hydrochloric Acid

HCID 12014802-Amino-4,6-difluoropyrimidine

HCID 391329903-(Chloromethyl)-2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridine

生成物 1

HCID 670287314,6-difluoro-N-((2-(4-fluorophenyl)-6-methylimidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-2-amine

出典と根拠

ORDレコード: ord-dd17c79b7b1e4a34b1d030dcb9e037f6
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…