Cyclopropanemethanamine → 2-Aminopyrimidine-4-carboxaldehyde (cyclopropylmethyl)imine

反応式

[NH2:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][N:3]=1.[CH2:10]1[CH2:12][CH:11]1[CH2:13][NH2:14]>>[CH:11]1([CH2:13][N:14]=[CH:8][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([NH2:1])[N:7]=2)[CH2:12][CH2:10]1

参加物

反応物 2

HCID 75646Cyclopropanemethanamine

HCID 178323462-Aminopyrimidine-4-carbaldehyde

生成物 1

HCID 861821762-Aminopyrimidine-4-carboxaldehyde (cyclopropylmethyl)imine

実験手順

2-Aminopyrimidine-4-carboxaldehyde and 2-cyclopropylmethyl amine were reacted by the procedure of example 1(c) to afford the title compound as a yellow oil.

出典と根拠

ORDレコード: ord-57fbc7e417b54453bc2e1a69ea483fae
出典データセット: uspto-grants-1997_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05593991

反応ノート

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