Hydroxide → (5-{2-[2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-ethoxy}-indol-1-yl)-acetic acid

反応式

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][c:13]([O:17][CH2:18][CH2:19][c:20]3[c:21]([CH3:36])[n:22][c:23](-[c:26]4[cH:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]4)[cH:24][cH:25]3)[cH:14][cH:15][c:16]12)=[O:37].[Li+:39].[OH-:38]>>[O:5]=[C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][c:13]([O:17][CH2:18][CH2:19][c:20]3[c:21]([CH3:36])[n:22][c:23](-[c:26]4[cH:27][cH:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]4)[cH:24][cH:25]3)[cH:14][cH:15][c:16]12)[OH:37]

参加物

反応物 3

HCID 961Hydroxide

HCID 28486Lithium ion

HCID 69642331(5-{2-[2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-ethoxy}-indol-1-yl)-acetic acid tert-butyl ester

生成物 1

HCID 22250824(5-{2-[2-Methyl-6-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-ethoxy}-indol-1-yl)-acetic acid

出典と根拠

ORDレコード: ord-121ae4e9881f4c588446cd70fbc47e13
出典データセット: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

反応ノート

読み込み中…