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Cornforth reagent → 5-Bromo-2-ethoxybenzaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Cornforth reagent | HCID 2724130 | — |
| 反応物 | 5-Bromo-2-ethoxybenzyl alcohol | HCID 24721639 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 5-Bromo-2-ethoxybenzaldehyde | HCID 144901 | — |
反応手順
5-Bromo-2-ethoxybenzyl alcohol (2.78 g, 12.0 mmol) and pyridinium dichromate (4.51 g, 12.0 mmol) in 120 ml of CH2Cl2 was stirred at RT for 6 h. The mixture was filtered, washed with H2O, 0.5 N HCl and brine and dried over Na2SO4. The product was purified by silica gel column chromatography (EtOAc/petroleum ether 10:100) to give 5-bromo-2-ethoxybenzaldehyde.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05593993 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-0e694943e7e64ef7ba6ea70287103c46 |
| 出典メモ | uspto-grants-1997_01 |