Tranylcypromine, cis- → (+)-N-(cis-2-phenylcyclopropyl)-N'-(5-chloropyrid-2-yl)thiourea
反応式
[C:1]1([C@H:7]2[CH2:9][C@H:8]2[NH2:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:11][C:12]1[CH:13]=[CH:14][C:15]([NH:18][C:19](N2C=CN=C2)=[S:20])=[N:16][CH:17]=1>>[C:1]1([C@H:7]2[CH2:9][C@H:8]2[NH:10][C:19]([NH:18][C:15]2[CH:14]=[CH:13][C:12]([Cl:11])=[CH:17][N:16]=2)=[S:20])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
3
実験手順
(-)-N-cis-2-phenylcyclopropylamine (0.23 g, 1.7 mmol) from Example 423 was condensed with 1-(5-chloropyrid-2-yl-thiocarbamoyl)-imidazole (0.4 g, 1.7 mmol) according to the procedure of Example 372 to yield the titled product as crystals.
出典と根拠
- ORDレコード
- ord-2930949b6fcd4e8296d9d66cd582537e
- 出典データセット
- uspto-grants-1997_01
- 特許番号
- US05593993
反応ノート
読み込み中…