Dimethyl Sulfoxide → 2-(4-((2-Amino-4-methyl-6-(pentylamino)pyrimidin-5-yl)methyl)phenyl)acetonitrile

反応式

[CH3:27][S:28]([CH3:29])=[O:30].[Cl:4][CH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:10][c:11]2[c:12]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[n:13][c:14]([NH2:18])[n:15][c:16]2[CH3:17])[cH:25][cH:26]1.[K:1][C:2]#[N:3].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[C:2](#[N:3])[CH2:5][c:6]1[cH:7][cH:8][c:9]([CH2:10][c:11]2[c:12]([NH:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[n:13][c:14]([NH2:18])[n:15][c:16]2[CH3:17])[cH:25][cH:26]1