化工社化工社 化学情報印刷レポート · 研究参考用
Water → HCID 178418251、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Butyl-4-chloro-5-(hydroxymethyl)imidazole | HCID 2735662 | — |
| 触媒 | HCID 178418406 | HCID 178418406 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | HCID 178418251 | HCID 178418251 | 86.3% |
反応手順
A stirred mixture of 2-n-butyl-4-chloro-5-hydroxymethylimidazole (15.00 g, 0.0795 mol) and activated manganese dioxide (40.00 g) in 600 ml of methylene chloride was refluxed for 24 h using a water separator. The mixture was filtered hot through a Celite® pad. The Celite® pad was washed several times with hot methylene chloride. The washings were combined with the filtrate and concentrated in vacuo to give 12.81 g (86%) of the aldehyde as a white solid; mp 97°-98° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05728842 |
| 出典データセット | uspto-grants-1998_03 |
| ORD ID | ord-0fdf59899d7d46d0ae418ee316a592b9 |
| 出典メモ | uspto-grants-1998_03 |