化工社化工社 化学情報印刷レポート · 研究参考用
Boronic acid, (4-ethylphenyl)- → N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Boronic acid, (4-ethylphenyl)- | HCID 2734352 | — |
| 反応物 | N-(5-bromothiophenesulfonyl)pyrrole | HCID 23445587 | — |
| 生成物 | N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole | HCID 23445382 | 81% |
反応手順
N-[5-(4-ethylphenyl)thiophene-2-sulfonyl]pyrrole was prepared, in the same manner as described in Example 32C, from 4-ethylphenylboronic acid and N-(5-bromothiophenesulfonyl)pyrrole. Purification by column chromatography using 10% ethyl acetate/hexanes gave the pure sulfonamide as a tan solid in 81% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05594021 |
| 出典データセット | uspto-grants-1997_01 |
| ORD ID | ord-3cfad4bb7beb4ac99de8b03712869ff0 |
| 出典メモ | uspto-grants-1997_01 |